| Main Title |
Letter from Socma to Usepa Submitting Information Concerning Tributyl Phosphate When Administered in the Diet of Rats in a 24-month Oncogenicity Study with Attachment. |
| CORP Author |
; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1991 |
| Report Number |
89-910000154 |
| Stock Number |
OTS0526409-3 |
| Additional Subjects |
Toxicology ;
Health effects ;
Tributyl Phosphate ;
Chronic Toxicity ;
Mammals ;
Rats ;
Oral ;
Diet ;
Toxic substances ;
Laboratory animals ;
CAS No 126-73-8
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0526409-3 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
4p |
| Abstract |
Preliminary results from an oncogenicity study in rats revealed subchronic toxic effects of tributyl phosphate (CAS No. 126-73-8). Groups of rats (50/sex/exposure group, strain not reported) were exposed in the diet at concentrations of 0, 200, 700 and 3000 ppm. A single high-dose female rat died on day 43 of the study. Gross necropsy findings included two 0.6 cm calculi in the urinary bladder which was distended with yellow fluid, dilated renal pelvis with multiple embedded white pinpoint foci, an ocular opacity, and dark red lungs. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1991 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A01/MF A01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028802760 |
| Origin |
NTIS |
| Type |
CAT |
