Main Title |
Cytotoxicity of Halogenated Alkanes in Primary Cultures of Rat Hepatocytes from Normal, Partial Hepatectomized, and Preneoplastic/Neoplastic Liver. |
Author |
Chang, L. W. ;
Pereira, M. A. ;
Klaunig, J. E. ;
|
CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. ;Medical Coll. of Ohio at Toledo. |
Year Published |
1985 |
Report Number |
EPA/600/J-85/219; |
Stock Number |
PB86-121506 |
Additional Subjects |
Halogen organic compounds ;
Toxicity ;
Environmental surveys ;
Bioassay ;
Biochemistry ;
Laboratory animals ;
Risk ;
Metabolism ;
Rats ;
Exposure ;
Hazardous materials ;
Cultures(Biology) ;
Chloroform ;
Liver neoplasms ;
Reprints ;
Toxic substances ;
Environmental health ;
Carcinogenesis ;
Ethane/dibromo ;
Ethane/dichloro ;
Ethane/trichloro
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB86-121506 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
12p |
Abstract |
Six halogenated hydrocarbons: chloroform, 1,2-dibromoethane (1,2-DBE), 1,1-dichloroethane (1,1-DCE), 1,2-dichloroethane (1,2DCE), 1,1,1-trichloroethane (1,1,1-TCE) and 1,1,2-trichloroethane (1,1,2-TCE) were evaluated for their cytotoxicity in primary cultures of rat hepatocytes isolated from normal, partial hepatectomized and from preneoplastic/neoplastic rat liver. None of the six halogenated alkanes exhibited any difference in their cytotoxicity toward hepatocytes isolated from normal liver or from liver containing preneoplastic/neoplastic lesions induced by either procedure. |
Supplementary Notes |
Pub. in Toxicology and Applied Pharmacology 80, p274-283 1985. Prepared in cooperation with Medical Coll. of Ohio at Toledo. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Cytotoxicity of Halogenated Alkanes in Primary Cultures of Rat Hepatocytes from Normal, Partial Hepatectomized, and Preneoplastic/Neoplastic Liver. |
PUB Date Free Form |
c1985 |
Category Codes |
6T; 6E; 57Y; 68G; 57U |
NTIS Prices |
Not available NTIS |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
604416604 |
Origin |
NTIS |
Type |
CAT |