||DDT Metabolism: Oxidation of the Metabolite 2,2-bis(p-Chlorophenyl)ethanol by Alcohol Dehydrogenase.
Suggs, Joseph E. ;
Hawk, Robert E. ;
Curley, August ;
Boozer, Elizabeth L. ;
McKinney., James D. ;
||Food and Drug Administration, Atlanta, Ga. Atlanta Toxicology Branch. ;National Inst. of Environmental Health Sciences, Research Triangle Park, N.C.
Chlorine organic compounds ;
Toxic substances ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||A metabolite of DDT, 2,2-bis(p-chlorophenyl)ethanol, is a substrate of crystalline liver alcohol dehydrogenase. The oxidation of the substrate was detected spectrophotometrically. The p-nitrophenylhydrazone derivative of the product, 2,2-bis(p-chlorophenyl)acetaldehyde, was identified by comparing its mass spectrum and thin-layer chromatographic behavior with that of an authentic sample.
||Pub. in the American Association for the Advancement of Science, v168 p582, 1 May 70. Prepared in cooperation with National Inst. of Environmental Health Sciences, Research Triangle Park, N.C.
||Included in the report, Journal Articles on Toxicology. Group 3, PB-278 081.
||Reprint: DDT Metabolism: Oxidation of the Metabolite 2,2-bis(p-Chlorophenyl)ethanol by Alcohol Dehydrogenase,
|PUB Date Free Form
||16 Feb 70
||6T; 57Y; 68E; 68G
||(Order as PB-278 081, MF A01)