Main Title |
Long-Term Stability of the Elemental Composition in Biological Materials. |
Author |
Zeisler, R. ;
Greenberg, R. ;
Stone, S. ;
Sullivan, T. ;
|
CORP Author |
National Bureau of Standards (NML), Gaithersburg, MD. Inorganic Analytical Research Div.;Environmental Protection Agency, Washington, DC. |
Publisher |
1988 |
Year Published |
1988 |
Stock Number |
PB89-156939 |
Additional Subjects |
Chemical analysis ;
Biological surveys ;
Tissue extracts ;
Standards ;
Concentration(Composition) ;
Chemical stabilization ;
Neutron activation analysis ;
Zinc ;
Selenicum ;
Arsenic ;
Trace elements ;
Liver extracts ;
Reprints ;
Standard reference materials
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB89-156939 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
4p |
Abstract |
Lyophilized and radiation sterilized biological certified reference materials (CRMs) are believed to be stable in their chemical composition. Generally, the certifying agencies consider the certificates of these biological CRMs valid for a 5-year shelf life, i.e., apart from measurable moisture content, the chemical composition should not change during that time. The long-term behavior of fresh frozen material is not known. In the study the elemental compositions of the Bovine Liver Standard Reference Material (SRM 1577) and human liver tissue samples are evaluated over a time period of more than 7 years. The concentrations of selected elements were determined by neutron activation analysis at various times. The initial evaluation of zinc, selenium and arsenic results gives no indication of changes during 7 years storage of fresh frozen tissues, however, a trend towards lower arsenic concentrations has been observed in SRM 1577 during a 10-year period. |
Supplementary Notes |
Sponsored by Environmental Protection Agency, Washington, DC. |
Availability Notes |
Pub. in Fresenius' Zeitschrift fuer Analytische Chemie 332, p612-615 1988. |
NTIS Title Notes |
Final rept.. |
Title Annotations |
Reprint: Long-Term Stability of the Elemental Composition in Biological Materials. |
Category Codes |
99A; 99F; 57B |
NTIS Prices |
Not available NTIS |
Primary Description |
NBS-120 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
911825751 |
Origin |
NTIS |
Type |
CAT |