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OLS Field Name OLS Field Data
Main Title Histological Progression of Hepatic Neoplasia in Rainbow Trout ('Salmo gairdneri').
Author Hendricks, J. D. ; Meyers, T. R. ; Shelton, D. W. ;
CORP Author Oregon State Univ., Corvallis. Agricultural Experiment Station.;Environmental Research Lab., Gulf Breeze, FL.
Year Published 1984
Report Number EPA/600/J-84/237;
Stock Number PB85-169688
Additional Subjects Trout ; Animal diseases ; Liver neoplasms ; Histology ; Adaptation ; Malignant neoplasms ; Carcinoma ; Exposure ; Tumors ; Photomicrographs ; Cells(Biology) ; Reprints ; Lesions ; Salmo gairdneri
Library Call Number Additional Info Location Last
NTIS  PB85-169688 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/21/1988
Collation 21p
Abstract The histological progression of hepatic neoplasia has not been as systematically studied in rainbow trout as it has been in rodents. Two putative preneoplastic lesions have been identified, the eosinophilic focus and the basophilic focus, but whether these correspond to similar lesions in rodent livers is not known. Preneoplastic liver lesions in rodents have been extensively characterized histochemically, but adaptation of these techniques to trout livers has not always been successful. Attempts at differentiation between benign and malignant liver lesions appear arbitrary. The authors believe the best classification of the neoplastic liver lesion is trout in a hepatocellular carcinoma because the potential for malignant behavior always exists and, with sufficient time, can often be histologically demonstrated. The authors have also described our experience with the characteristics of other liver lesions associated with hepatocarcinogenesis.
Availability Notes Pub. in National Cancer Institute Monograph 65, p321-336 May 84.
NTIS Title Notes Journal article.
Title Annotations Reprint: Histological Progression of Hepatic Neoplasia in Rainbow Trout ('Salmo gairdneri').
PUB Date Free Form c1984
Category Codes 6C; 57Z; 98F
NTIS Prices Not available NTIS
Primary Description 600/04
Document Type NT
Cataloging Source NTIS/MT
Control Number 514424062
Origin NTIS
Type CAT