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OLS Field Name OLS Field Data
Main Title Summary of the EPA workshop on carcinogenesis bioassay via the dermal route : April 28-29, 1987, Washington, D.C. /
CORP Author Dynamac Corp., Rockville, MD.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher Reproduced by U.S. Dept. of Commerce, National Technical Information Service,
Year Published 1987
Report Number EPA 560/6-89-002; EPA-68-01-7266
Stock Number PB90-146309
OCLC Number 25057402
Subjects Skin absportion--Physiological aspects--Congresses. ; Carcinogenesis--Congresses.
Additional Subjects Meetings ; Skin(Anatomy) ; Toxicity ; Acrylates ; Bioassay ; Methacrylates ; Laboratory animals ; Carcinogenicity tests ; Environmental exposure pathways ; Chemical effluents ; Pharmacokinetics ; Dose-response relationships
Internet Access
Description Access URL
Local Library Info
Library Local Subject Local Note
EKB Library copy is an earlier, typescript version with no publication information.
Library Call Number Additional Info Location Last
EJED  EPA-560/6-89-002 OCSPP Chemical Library/Washington,DC 01/10/1992
EKBD  EPA 560/6-89-002 Research Triangle Park Library/RTP, NC 08/04/2014
NTIS  PB90-146309 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation 8 leaves
Abstract Traditionally, the oral route has been the most common route of administration in bioassays which tested the potential carcinogenicity of chemicals. Regulatory agencies, however, prefer to have test chemicals applied by the same route as expected human exposure, whenever possible. Since human exposure to industrial chemicals is frequently via the dermal route, this has become a route of choice for animal testing of certain chemicals. However, protocol design for dermal bioassays presents many unique problems which must be addressed before guidelines for bioassays by the dermal route can be formulated. Furthermore, it may be feasible to develop a limited dermal protocol to screen certain classes of chemicals such as acrylates/methacrylates. Recognizing the need for this workshop, it was designed in two distinct parts; to address the problems inherent in the development of a generic protocol for dermal bioassays and, a specific limited dermal bioassay protocol for acrylates/methacrylates.
Notes Includes bibliographical references. "EPA 560/6-89-002." Sponsored by the Office of Toxic Substances, U.S. Environmental Protection Agency.
Place Published Springfield, VA
Supplementary Notes Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Corporate Au Added Ent Dynamac Corporation.; United States. Environmental Protection Agency. Office of Toxic Substances.
Conference Title Workshop on Carcinogenesis Bioassay Via the Dermal Route
PUB Date Free Form 1987
NTIS Prices PC A02/MF A01
BIB Level m
Medium unmediated
Content text
Carrier volume
Cataloging Source OCLC/T
OCLC Time Stamp 20160524115818
Language eng
Origin OCLC
OCLC Rec Leader 01536cam 2200337Ka 45020