| Main Title |
Oral Toxicity in Rats Test Results with Cover Letter Dated 12/17/1982. |
| CORP Author |
Mb Research Laboratories, Inc.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1982 |
| Report Number |
40-8258074 |
| Stock Number |
OTS0514286 |
| Additional Subjects |
Toxicology ;
Health effects ;
1 ;
2 ;
4-trimethylbenzene ;
Acute Toxicity ;
Mammals ;
Rats ;
Oral ;
Gavage ;
Toxic substances ;
Laboratory animals ;
CAS No 95-63-6
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0514286 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
6p |
| Abstract |
Acute oral toxicity was evaluated in groups of 10 male Wistar rats administered single doses of 98% pseudocumene by oral gavage at levels of 3.51, 5.0, 7.12 and 10.14 g/kg of body weight. Mortality was observed in 3 animals in the 5.0 g/kg dose group, 7 in the 7.12 g/kg dose group, and all 10 in the highest dose group. The LD50 value was calculated to be 6.0 g/kg of body weight, with confidence limits of 4.92 - 7.32 g/kg, by the Litchfield and Wilcoxon method. Clinical observations included lethargy, ptosis, ataxia, and piloerection. Gross necropsy findings were not reported. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1982 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A02/MF A02 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028801930 |
| Origin |
NTIS |
| Type |
CAT |
