||Teratologic Evaluation of Inhaled Ethyl Acrylate in Rats with Attachments and Cover Letter Dated 07/17/1989 (Sanitized).
||Dow Chemical Co., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Health effects ;
Ethyl Acrylate (140-88-5) ;
Reproduction/fertility Effects ;
Toxic substances ;
Laboratory animals ;
CAS No 140-88-5
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||Developmental toxicity was evaluated in groups of 33 female Sprague-Dawley rats receiving whole-body exposure to ethyl acrylate at vapor concentrations of 0, 50, or 150 ppm, for 6 hours/day on gestation days 6-15, followed by fetal examination on gestation day 21. High-dose dams had decreased body weight gain and food consumption, and increased water consumption. The compound was not embryotoxic or fetotoxic. The was a small increase in fetal malformations in the high-dose group, but the difference was not significant.
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||57Y; 57U; 68G; 99; 44G
||PC A03/MF A03