Full Record Display for the EPA National Library Catalog

RECORD NUMBER: 678 OF 1240

OLS Field Name OLS Field Data
Main Title Metabolism and DNA Adduct Formation of 2-Acetylaminofluorene by Bladder Explants from Human, Dog, Monkey, Hamster and Rat.
Author Schut, H. A. J. ; Daniel, F. B. ; Schenck, K. M. ; Loeb, T. R. ; Stoner, G. D. ;
CORP Author Medical Coll. of Ohio at Toledo.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1984
Report Number EPA/600/J-84/164;
Stock Number PB85-146801
Additional Subjects Environmental surveys ; Biochemistry ; Malignant neoplasms ; Toxicology ; Metabolism ; Deoxyribonucleic acids ; Bladders ; Amines ; Laboratory animals ; Dogs ; Monkeys ; Rats ; Aromatic compounds ; Industrial hygiene ; Chemical bonds ; Reprints ; Cancer ; Occupational safety and health ; Fluorene/acetyl-amino
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB85-146801 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 8p
Abstract It is concluded that bladder explants of the human, dog, monkey, hamster, and rat metabolize AAF mainly to ring-hydroxylated products, but also form small amounts of the proximate carcinogenic metabolite N-hydroxy-AAF. Neither the overall binding of AAF to bladder DNA, nor the formation of specific AAF-DNA adducts is correlated with the relative susceptibilities of these five species to aromatic amine-induced urinary bladder carcinogenesis.
Availability Notes Pub. in Carcinogenesis, v5 n10 p1287-1292 1984.
NTIS Title Notes Journal article.
Title Annotations Reprint: Metabolism and DNA Adduct Formation of 2-Acetylaminofluorene by Bladder Explants from Human, Dog, Monkey, Hamster and Rat.
PUB Date Free Form c1984
Category Codes 6A; 6T; 7D; 68G; 57B; 57Y; 99F; 41I; 94D
NTIS Prices Not available NTIS
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 510224080
Origin NTIS
Type CAT