Main Title |
Molecular modeling : basic principles and applications / |
Other Authors |
|
Publisher |
Wiley-VCH, |
Year Published |
2008 |
OCLC Number |
191889943 |
ISBN |
9783527315680; 3527315683 |
Subjects |
Biomolecules--Structure--Computer simulation ;
Proteins--Structure--Computer simulation ;
Molecules--Models--Computer simulation ;
Drugs--Design--Computer simulation ;
Ligand binding (Biochemistry)--Computer simulation ;
Molekulardesign--(DE-588)4265444-0 ;
Molekylstruktur--datorsimulering ;
Proteinbindning
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
ELBM |
QP517.M3H54 2008 |
|
AWBERC Library/Cincinnati,OH |
01/05/2015 |
|
Edition |
3rd rev. and expanded ed. |
Collation |
x, 310 p. : ill. (some col.) ; 24 cm. |
Notes |
Previous ed.: Weinheim: VCH, 2003. Includes bibliographical references and index. |
Contents Notes |
Introduction -- Small molecules -- A case study for small molecule modeling: dopamine D3, receptor antagonists -- Introduction to comparative protein modeling -- Virtual screening and docking -- Scope and limits of molecular docking -- Chemogenomic approaches to rational drug design -- A case study for protein modeling: the nuclear hormone receptor CAR as an example for comparative modeling and the analysis of protein-ligand complexes. "Ideal for beginners, this book explains the basics of modeling in a competent yet easily understandable way, with completely worked-out examples to guide readers to their first modeling experiments. This third edition features a new chapter on chemogenomics, reflecting the trend towards 'chemical biology', while the example of protein modeling is completely rewritten for a better 'feel' of modeling complex biomolecules. The authors are experienced university lecturers who regularly hold courses on molecular modeling, making this a tried-and-tested text for teachers. It is equally valuable for experts, since it is the only book to evaluate the strengths and limitations of the molecular modeling techniques and software currently available."--Jacket. |
Place Published |
Weinheim |
Title Ser Add Ent |
Methods and principles in medicinal chemistry ; v. 5. |
PUB Date Free Form |
c2008 |
Series Title Untraced |
Methods and principles in medicinal chemistry ; v. 5 |
BIB Level |
m |
Cataloging Source |
OCLC/T |
LCCN |
2008531099 |
Merged OCLC records |
166315560 |
OCLC Time Stamp |
20141230131338 |
Language |
eng |
Origin |
OCLC |
Type |
CAT |
OCLC Rec Leader |
04506cam 2200841 a 45020 |