Full Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Cell Stress Proteins [electronic resource] /
Author Calderwood, Stuart K.
Publisher Springer New York,
Year Published 2007
Call Number QR1-502
ISBN 9780387397177
Subjects Life sciences. ; Immunology. ; Biochemistry. ; Microbiology.
Internet Access
Description Access URL
Collation XV, 459 p. online resource.
Notes Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes Introduction: Heat Shock Proteins-From Drosophila Stress Proteins to Mediators of Human Disease -- Introduction: Heat Shock Proteins-From Drosophila Stress Proteins to Mediators of Human Disease -- Stress Response and Molecular Chaperones -- Biology of the Heat Shock Response and Stress Conditioning -- Bacterial Stress Sensors -- Unfolded Protein Response: Contributions to Development and Disease -- Molecular Mechanisms of Stress Protein Expression -- Genetic Models of HSF Function -- HSF1 and HSP Gene Regulation -- Cellular Stress Proteins -- Small Heat Shock Proteins in Physiological and Stress-Related Processes -- Large Mammalian hsp70 Family Proteins, hsp110 and grp170, and Their Roles in Biology and Cancer Therapy -- Molecular Chaperones and Protein Folding -- Regulation of Hsp70 Function: Hsp40 Co-Chaperones and Nucleotide Exchange Factors -- Protein Disassembly by Hsp40-Hsp70 -- Mammalian HSP40/DnaJ Chaperone Proteins in Cytosol -- Role of Molecular Chaperones in Cell Regulation -- FKBP Co-Chaperones in Steroid Receptor Complexes -- Up and Down Regulation of the Stress Response by the Co-Chaperone Ubiquitin Ligase CHIP -- Role of Cdc37 in Protein Kinase Folding -- Intracellular and Extracellular Stress Proteins in Human Disease -- Targeting Hsp90 in Cancer and Neurodegenerative Disease -- gp96 and Tumor Immunity -- Immunoregulatory Activities of Extracellular Stress Proteins -- Heat Shock Proteins and Neurodegenerative Diseases -- Heat Shock Proteins in the Progression of Cancer. This comprehensive volume, written by experts in the field, provides a current understanding of the molecular properties of the heat shock proteins and their roles in health and disease. Cell Stress Proteins includes advances in several aspects of stress protein research, with chapters ranging from basic studies of the role of heat shock proteins in protein folding to reviews examining the breakdown of stress protein regulation during disease. It also provides analysis of the biochemical and molecular properties of heat shock proteins which can be utilized in evaluating their role in human physiology and pathology. Cell Stress Proteins is an ideal book for researchers, clinicians, physicians, and graduate students in the fields of biochemistry, cell biology, microbiology, immunology, and genetics.
Place Published New York, NY
Corporate Au Added Ent SpringerLink (Online service)
Title Ser Add Ent Protein Reviews ; 7
Host Item Entry Springer eBooks
PUB Date Free Form 2007
Series Title Untraced Protein Reviews ; 7
BIB Level m
Medium computer
Content text
Carrier online resource
Cataloging Source OCLC/T
OCLC Time Stamp 20131220070200
Language eng
OCLC Rec Leader 03750nam a22004695i 45