Main Title |
Substituent Contribution to the Partition Coefficients of Substituted Benzenes in Solvent-Water Mixtures. |
Author |
Chiou, Cary T. ;
Schmedding, David W. ;
Block, John H. ;
Manes, Milton ;
|
CORP Author |
Oregon State Univ., Corvallis. Environmental Health Sciences Center. ;Kent State Univ., OH. Dept. of Chemistry.;Corvallis Environmental Research Lab., OR. |
Year Published |
1982 |
Report Number |
EPA-R-808046; EPA-600/J-82-333; |
Stock Number |
PB83-223826 |
Additional Subjects |
Organic compounds ;
Octanol ;
Physicochemical properties ;
Mixtures ;
Reprints ;
Partition coefficients ;
Benzene ;
Biological processes ;
Numerical solution
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB83-223826 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
5p |
Abstract |
In the course of correlation analysis for biological activities, octanol-water partition coefficients (P) have been used widely to express the lipophilic interactions of organic compounds with biological substrates. Since discrepancies are found between some pi values from different parent compounds and these variations depend also on the nature of the solvent-water system being used, it is of interest to examine the relationship between and pertinent physicochemical properties to identify the factors that account for the discrepancies. |
Supplementary Notes |
Prepared in cooperation with Kent State Univ., OH. Dept. of Chemistry. |
Availability Notes |
Pub. in Jnl. of Pharmaceutical Sciences, v71 n11 p1307-1309 1982. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Substituent Contribution to the Partition Coefficients of Substituted Benzenes in Solvent-Water Mixtures. |
PUB Date Free Form |
c1982 |
Category Codes |
7D; 6A; 99F; 57B |
NTIS Prices |
Not available NTIS |
Primary Description |
600/02 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
325925174 |
Origin |
NTIS |
Type |
CAT |