Main Title |
Effects of Segregation and Selection on Instability of Plasmid pACYC184 in 'Escherichia coli'B. |
Author |
Lenski, R. E. ;
Bouma, J. E. ;
|
CORP Author |
California Univ., Irvine. Dept. of Ecology and Evolutionary Biology.;Environmental Research Lab., Gulf Breeze, FL. |
Year Published |
1987 |
Report Number |
EPA-R-813401; EPA/600/J-87/311; |
Stock Number |
PB88-196241 |
Additional Subjects |
Tolerances(Physiology) ;
Bacteria ;
Cell division ;
Antibiotics ;
Escherchi coli ;
Mathematical models ;
Selection ;
Deoxyribonucleic acids ;
Populations ;
Dynamics ;
Plasmids ;
Hosts
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB88-196241 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
5p |
Abstract |
The authors use a mathematical model to analyze the dynamics of loss of nonconjugative pACYC184 from populations of Escherichia coli B in glucose-limited continuous culture. The model incorporates both plasmid segregation and selection against plasmid carriage. It is concluded that there is intense selection against plasmid carriage (s = 0.3 per culture generation), which amplifies the frequency of segregants arising de novo. (Copyright (c) 1987, American Society for Microbiology.) |
Supplementary Notes |
Pub. in Jnl. of Bacteriology, v169 n11 p5314-5316 Nov 87. Sponsored by Environmental Research Lab., Gulf Breeze, FL. |
NTIS Title Notes |
Journal article. |
PUB Date Free Form |
c1987 |
Category Codes |
57K; 57 |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/04 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
817624593 |
Origin |
NTIS |
Type |
CAT |