Main Title |
Initial Submission: Acute Oral Toxicity of 1,2,4-benzen Tricarboxylic Acid, Trimethyl Ester in Rats with Cover Letter dated 08/29/92. |
CORP Author |
Du Pont de Nemours (E.I.) and Co., Newark, DE. Haskell Lab. for Toxicology and Industrial Medicine.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
Year Published |
1992 |
Report Number |
88-920008903 |
Stock Number |
OTS0570948 |
Additional Subjects |
Toxicology ;
Health effects ;
1 ;
2 ;
4-benzen Tricarboxylic Acid ;
Trimethyl Ester ;
Acute Toxicity ;
Mammals ;
Rats ;
Oral ;
Gavage ;
Toxic substances ;
Laboratory animals ;
CAS No 2459-10-1
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Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
OTS0570948 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
13p |
Abstract |
Trimethyl 1,2,4-benzenetricarboxylate (CAS No. 2459-10-1) was evaluated for acute oral toxicity. The test substance was administered by intragastric intubation to young adult ChR-CD male rats. Dosage levels and mortality data are as follows: 10,000 (0/10); 11,000 (4/10); 12,000 (4/10); and 14,000 mg/kg of body weight (8/10), with all deaths occurring 4-days after dosing. Clinical signs at 10,000 mg/kg and above included salivation, weakness, stained and wet perineal area, stained face, pallor, chromodacryorrhea, and moderate weight loss. The LD50 was determined to be 12,232 mg/kg b.w. |
Supplementary Notes |
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Availability Notes |
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PUB Date Free Form |
1992 |
Category Codes |
57Y; 57U; 68G; 99; 44G |
NTIS Prices |
PC A03/MF A03 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
028803990 |
Origin |
NTIS |
Type |
CAT |