| Main Title |
Support: Letter from (Confidential) to USEPA reporting Results of Acute Oral Toxicity Study (LD50) in Rats with (Confidential), a Substituted Heterocycle, dated 08/29/1995. (Sanitized). |
| CORP Author |
; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1995 |
| Report Number |
8EHQ-0895-8733S |
| Stock Number |
OTS0538409-9 |
| Additional Subjects |
Toxicology ;
Health effects ;
Toxic substances ;
Cymoxanil ;
Substituted heterocycle ;
Rats ;
Acute toxicity ;
Mammals ;
Oral ;
Gavage ;
CAS No 57966-95-7
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0538409-9 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
6p |
| Abstract |
The test substance was administered by intragastric intubation to 1 group of 5 male rats at a dosage of 5000 mg/kg and 3 groups of 5 female rats at dosages of 1000, 3000, or 5000 mg/kg. Surviving rats were weighed and observed for mortality or clinical signs of toxicity over a 14-day observation period. All rats were subjected to gross pathology after death or after the 14-day observation period. No deaths occurred in male rats dosed at 5000 mg/kg; spasms were observed in 1 of these rats during the study. AII female rats dosed at 5000 mg/kg died during the study. Ataxia was observed in one of these rats on the day of dosing, and this rat was found dead the day after dosing. Two rats dosed at 3000 mg/kg died during the study. One of these rats exhibited tremors on test days 2 to 4 and was found dead on test day 5. Another rat dosed at 3000 mg/kg exhibited ataxia on test days 2 and 3; this rat survived to study completion. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
31 Aug 1995 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A02/MF A02 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
018801110 |
| Origin |
NTIS |
| Type |
CAT |
