| Main Title |
Initial Submission: Acute Oral Toxicity of 1,2,4-benzen Tricarboxylic Acid, Trimethyl Ester in Rats with Cover Letter dated 08/29/92. |
| CORP Author |
Du Pont de Nemours (E.I.) and Co., Newark, DE. Haskell Lab. for Toxicology and Industrial Medicine.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1992 |
| Report Number |
88-920008903 |
| Stock Number |
OTS0570948 |
| Additional Subjects |
Toxicology ;
Health effects ;
1 ;
2 ;
4-benzen Tricarboxylic Acid ;
Trimethyl Ester ;
Acute Toxicity ;
Mammals ;
Rats ;
Oral ;
Gavage ;
Toxic substances ;
Laboratory animals ;
CAS No 2459-10-1
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0570948 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
13p |
| Abstract |
Trimethyl 1,2,4-benzenetricarboxylate (CAS No. 2459-10-1) was evaluated for acute oral toxicity. The test substance was administered by intragastric intubation to young adult ChR-CD male rats. Dosage levels and mortality data are as follows: 10,000 (0/10); 11,000 (4/10); 12,000 (4/10); and 14,000 mg/kg of body weight (8/10), with all deaths occurring 4-days after dosing. Clinical signs at 10,000 mg/kg and above included salivation, weakness, stained and wet perineal area, stained face, pallor, chromodacryorrhea, and moderate weight loss. The LD50 was determined to be 12,232 mg/kg b.w. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
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| PUB Date Free Form |
1992 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A03/MF A03 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028803990 |
| Origin |
NTIS |
| Type |
CAT |
