||Initial Submission: Letter from (Confidential Source) to USEPA Reporting Results in Acute Dermal Toxicity Test of 2,6-Dichloroaniline in Rats, dated 08/06/1999. (Sanitized).
||; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Health effects ;
Laboratory animals ;
Toxic substances ;
Acute toxicity ;
Laboratory tests ;
Risk assessment ;
Acute dermal toxicity
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||Five male and female Fischer 344 rats were given either a single dermal application to provide a dose level of 2000, 2500 or 5000 mg/kg or a subcutaneous injection to provide a dose level of 2000 or 2500 mg/kg of the study compound dissolved in DMSO. Clinical observations indicate that at 5000 mg/kg dermal application whole body twitching was observed in the one surviving female rat and three of the five male rats were laterally recumbent with whol body twitching a the above dermal level.
||The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
||Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at firstname.lastname@example.org. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA.
|PUB Date Free Form
||10 Aug 1999
||57Y; 57U; 68G; 99
||PC A01/MF A01