Main Title |
Virus-Like Particles with T=19 Icosahedral Symmetry in a Human Gastroenteritis Stool. |
Author |
Williams, F. P. ;
|
CORP Author |
Health Effects Research Lab., Cincinnati, OH. |
Year Published |
1985 |
Report Number |
EPA/600/J-85/253; |
Stock Number |
PB86-156932 |
Additional Subjects |
Viruses ;
Gastroenteritis ;
Humans ;
Feces ;
Reprints ;
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB86-156932 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
8p |
Abstract |
Virus-like particles not previously described were observed in a human gastroenteritis stool using negative-stain TEM. The stool was among a number of acute-phase illness stools which had been collected in Egypt during 1980. The particles measured 65-70 nm in diameter, and it was possible to detect individual capsomers on many of these particles. The capsomeric pattern identified on the particles corresponded to an icosahedrally symmetric T = 19 capsid. Distinctive 5-fold vertices, usually appearing as darker spots on the capsid were an additional feature of these particles. The capsid structure, which is skew, could readily be distinguished from the T = 25 capsid of adenovirus and the holey capsids of rotavirus and reovirus. Antibody to the particles was detected in both the shedding individual's acute- and convalescent-phase serum specimens using IEM, although an antibody increase was not demonstrated. |
Supplementary Notes |
Pub. in Micron and Microscopica Acta, v16 n3 p173-178 Oct 85. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Virus-Like Particles with T=19 Icosahedral Symmetry in a Human Gastroenteritis Stool. |
PUB Date Free Form |
1985 |
Category Codes |
6E; 6M; 57E; 57K |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
611413247 |
Origin |
NTIS |
Type |
CAT |