||Some Effects of the Formamidine Pesticide Chlordimeform on the Behavior of Mice.
Landauer, M. R. ;
Tomlinson, W. T. ;
Balster, R. L. ;
MacPhail, R. C. ;
||Health Effects Research Lab., Research Triangle Park, NC.
Physiological effects ;
Laboratory animals ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||Three experiments were performed to determine the behavioral effects of acutely administered chlordimeform (1-56 mg/kg, i.p.) to male mice. In Experiment I, dosages of 30 and 56 mg/kg decreased the amount of time spent investigating a female conspecific. In Experiment II, large dosages of chlordimeform (30 and 56 mg/kg) decreased vertically directed activity (rearing) to a proportionately greater extent than horizontally directed activity (ambulation). In Experiment III, chlordimeform produced conditioned flavor aversions that were intermediate at 10 mg/kg and maximal at 30 mg/kg. In an additional experiment (Experiment IV), the LD50 for chlordimeform was determined to be 95.6 mg/kg. Behavioral effects were thus obtained at dosages that were approximately 10 to 30% of the LD50.
||Pub. in NeuroToxicology 5, n2 p91-100 1984.
|NTIS Title Notes
||Reprint: Some Effects of the Formamidine Pesticide Chlordimeform on the Behavior of Mice.
|PUB Date Free Form
||6T; 57Y; 68E
||Not available NTIS