Main Title |
Kinetic Study on the Inhibition of Hen Brain Neurotoxic Esterase by Mipafox. |
Author |
Soliman, Salah A. ;
Curley, August ;
|
CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1982 |
Report Number |
EPA-600/J-81-236; |
Stock Number |
PB83-209692 |
Additional Subjects |
Inhibitors ;
Esterases ;
Chickens ;
Brain ;
Reprints ;
Mipafox ;
Neurotoxins ;
Valerate/nitrophenyl
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB83-209692 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
7p |
Abstract |
A direct method of assaying neurotoxic esterase (NTE) activity, using 4-nitrophenyl valerate, has been described. The technique was used to determine the biomolecular rate (ki), phosphorylation (k2), and affinity (kd) constants for the reaction of hen brain microsomal NTE with mipafox. Results indicate that the new technique for assaying NTE makes detailed kinetic studies of NTE inhibition possible. |
Supplementary Notes |
Pub. in Journal of Analytical Toxicology, v6 p4-9 1982. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Kinetic Study on the Inhibition of Hen Brain Neurotoxic Esterase by Mipafox. |
PUB Date Free Form |
1982 |
Category Codes |
6T; 57Y |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
324622592 |
Origin |
NTIS |
Type |
CAT |