||Comparison of Mutagenic Activities of Several Peroxyacyl Nitrates.
Kleindienst, T. E. ;
Shepson, P. B. ;
Smith, D. F. ;
Hudgens, E. E. ;
Nero, C. M. ;
||NSI Technology Services Corp., Research Triangle Park, NC.;Environmental Protection Agency, Research Triangle Park, NC. Atmospheric Research and Exposure Assessment Lab.
Comparative evaluations ;
Dose-response relationships ;
Salmonella typhimurium ;
Mutagenicity tests ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||Salmonella typhimurium strain TA100 was exposed to a series of peroxyacyl nitrates including peroxyacetyl nitrate (PAN), peroxypropionyl nitrate (PPN), peroxybutyryl nitrate (PBN), peroxybenzoyl nitrate (PBzN), and chloroperoxyacetyl nitrate (CPAN). Gas phase concentrations for the individual exposures were in the high ppbv range. The dose was determined from the deposition rate and measured from the net decrease of the test compound in the exposure chamber and the exposure time. The mutagenic activity for each compound determined from the dose-response relationship gave values ranging from 250 (PBN) to 6570 (PBzN) revertants/micromol. The difficulties of quantifying the actual gas-phase chemical dose the bacteria are exposed to in this variant of the Ames Test are delineated. (Copyright (c) 1990 Wiley-Liss, Inc.)
||Pub. in Environmental and Molecular Mutagenesis, v16 p70-80 1990. Sponsored by Environmental Protection Agency, Research Triangle Park, NC. Atmospheric Research and Exposure Assessment Lab.
|NTIS Title Notes
||Reprint: Comparison of Mutagenic Activities of Several Peroxyacyl Nitrates.
||PC A03/MF A01