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RECORD NUMBER: 28 OF 90

OLS Field Name OLS Field Data
Main Title Dominant Lethal Effects of Subchronic Acrylamide Administration in the Male Long-Evans Rat.
Author Smith, M. K. ; Zenick, H. ; Preston, R. J. ; George, E. L. ; Long, R. E. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Cincinnati Univ., OH. Dept. of Environmental Health. ;Oak Ridge National Lab., TN.
Year Published 1986
Report Number EPA/600/J-86/059;
Stock Number PB86-204633
Additional Subjects Toxicology ; Bioassay ; Vinyl ; Dosage ; Acrylamide ; Neurotoxicity
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB86-204633 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/21/1988
Collation 7p
Abstract Acrylamide, a widely used vinyl monomer, is well known as a neurotoxin but inactive as a mutagen in bacterial test systems. The experiments reported demonstrate that after subchronic oral dosing in the male rat, acrylamide induced significant elevations in both pre and post implantation loss following dominant lethal testing. These effects were seen at doses which failed to produce clinical or pathological evidence of neurotoxicity.
Supplementary Notes Pub. in Mutation Research 173, p273-277 Mar 86. Prepared in cooperation with Cincinnati Univ., OH. Dept. of Environmental Health, and Oak Ridge National Lab., TN.
NTIS Title Notes Journal article.
PUB Date Free Form c1986
Category Codes 6T; 57Y
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 621324574
Origin NTIS
Type CAT