Main Title |
Synthesis of New Cyclopenta-Fused PAH (Polycyclic Aromatic Hydrocarbons) Isomers of Cata-Annelated Benzenoid Systems (Journal Version). |
Author |
Sangaiah, R. ;
Gold, A. ;
|
CORP Author |
North Carolina Univ. at Chapel Hill. School of Public Health.;Health Effects Research Lab., Research Triangle Park, NC. |
Publisher |
c1987 |
Year Published |
1987 |
Report Number |
EPA-R-811817; EPA/600/J-87/387; |
Stock Number |
PB89-101125 |
Additional Subjects |
Aromatic polycyclic hydrocarbons ;
Chemical reactions ;
Reprints ;
Benzaceanthrylene ;
Benzacephenanthrylene ;
CAS 19770-52-6 ;
CAS 16683-64-0 ;
CAS 216-48-8
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB89-101125 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
8p |
Abstract |
The syntheses of three new benz-annelated derivatives of aceanthrylene and acephenanthrylene are reported. These systems are of interest in studies on mechanisms of bioactivation and structure-activity correlations because of their predicted high level of biological activity. Of the three isomers, benz(d)aceanthrylene has been synthesized by two routes involving Friedel-Crafts acylations of 1,2,3,4-tetrahydronaphthacene with chloroacetyl chloride or oxalyl chloride as the key step. The cyclic ketone product from each route has been successfully elaborated. Synthesis of benz(k)aceanthrylene involves preparation of acenaphthene-3,4-di-carboxylic anthdride and its smooth conversion. A straightforward and high-yield synthesis of benz(j)acephenanthrylene is described utilizing a Robinson annelation reaction of methyl vinyl ketone with a previously reported ketonic precursor of acephenanthrylene. (Copyright (c) 1987 American Chemical Society.) |
Supplementary Notes |
Pub. in Jnl. of Organic Chemistry, v52 p3205-3211 1987. Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Synthesis of New Cyclopenta-Fused PAH (Polycyclic Aromatic Hydrocarbons) Isomers of Cata-Annelated Benzenoid Systems (Journal Version). |
Category Codes |
99D |
NTIS Prices |
Not available NTIS |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
834420754 |
Origin |
NTIS |
Type |
CAT |