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OLS Field Name OLS Field Data
Main Title Deposition of Sulfate Acid Aerosols in the Developing Human Lung.
Author Martonen, T. B. ; Zhang, Z. ; Hester, J. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Environmental Toxicology Div. ;ManTech Environmental Technology, Inc., Research Triangle Park, NC. ;Rhode Island Univ., Kingston. Dept. of Mechanical Engineering.
Publisher 1993
Year Published 1993
Report Number EPA/600/J-93/401;
Stock Number PB93-236388
Additional Subjects Air pollution effects(Humans) ; Lung ; Growth ; Respiratory function tests ; Deposition ; Trachea ; Bronchi ; Moisture ; Reprints ; Sulfate acid aerosols ; Hygroscopicity
Library Call Number Additional Info Location Last
NTIS  PB93-236388 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 11/22/1993
Collation 25p
Abstract Computations of aerosol deposition as affected by (1) aerosol hygroscopicity, (2) human age, and (3) respiratory intensity are accomplished using a validated mathematical model. The interactive effects are very complicated but systematic. Few general observations can be made; rather, the findings presented within should be addressed on a case-by-case basis. The behavior of inhaled H2SO4 particles subsequent to water vapor uptake significantly influences their total deposition values and relative spatial distribution patterns within tracheobronchial and pulmonary airways. These results must be accounted for in risk assessment protocols, since compartments of the lung have different clearance processes and sensitivities to toxic materials. There is a critical size in the 0.2-0.4 micrometer range: For larger particles the influence of hygroscopicity is to increase total deposition, whereas for smaller particles the opposite occurs. The dosimetric model was developed to provide a scientific basis for extrapolation modeling of factors (1), (2), and (3) in the hazard evaluation of airborne contaminants.
Supplementary Notes Pub. in Inhalation Toxicology 5, n1 p165-187 Feb 93. See also PB86-163383. Prepared in cooperation with ManTech Environmental Technology, Inc., Research Triangle Park, NC., and Rhode Island Univ., Kingston. Dept. of Mechanical Engineering.
NTIS Title Notes Journal article.
Title Annotations Reprint: Deposition of Sulfate Acid Aerosols in the Developing Human Lung.
Category Codes 68A; 68G; 57Y; 57S
NTIS Prices PC A03/MF A01
Primary Description 600/10
Document Type NT
Cataloging Source NTIS/MT
Control Number 330925771
Origin NTIS
Type CAT