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OLS Field Name OLS Field Data
Main Title Demonstration of Low Cost, Low Burden, Exposure Monitoring Strategies for Use in Longitudinal Cohort Studies. Volume 1. Final Report.
Author Rench, J. D. ; Raymer, J. H. ; Thalji, L. ; Spruill, M. ; Salmons, C. A. ;
CORP Author RTI International, Research Triangle Park, NC.;Environmental Protection Agency, Las Vegas, NV. National Exposure Research Lab.
Publisher Sep 2004
Year Published 2004
Report Number EPA-68-D-99-012; EPA/600/R-04/109;
Stock Number PB2005-108394
Additional Subjects Cohort studies ; Study methods ; Data collection ; Sampling ; Participant involvement ; Study design ; Questionaires ; Instructional materials ; Participation ; Methodology ; Quality assurance ; Recommendations ; National Children's Study
Library Call Number Additional Info Location Last
NTIS  PB2005-108394 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 07/12/2006
Collation 130p
Abstract The Federal Government is currently planning a large, prospective birth cohort study known as the National Children's Study that will potentially involve 100,000 children and their families. The observation period will start as close to conception as possible and will continue for 20 years after birth. Given the magnitude and expense of such a large study, sample collection methods that are amenable to acquisition of samples exclusively by the participants themselves followed by direct shipment to the analysis laboratory present a cost-effective alternative to technician-based sampling procedures. In this pilot study, the ability of participants in three age cohorts to collect environmental and biological samples according to prescribed protocols was evaluated. The cohorts consisted of parents and their children in the ages of 0-1 year, 3-5 years, and 6-8 years old. Biological and environmental samples collected during the study included urine, hair, saliva, breast milk, duplicate diet, tap water, vacuum cleaner dust, floor surface dust wipes, air samples, cotton sock dosimeters, and humidity/temperature measurements. Sample collection instructions and materials were prepared, subjected to evaluation and modification using a test population, and shipped to participants over a 12-month period. Participants were requested to collect the samples, complete questionnaires, and return the samples to the laboratory within defined time periods. Upon receipt at the laboratory, the condition of the samples was assessed by visual inspection and the details of the receipt and evaluation were logged into a computer database; queries were subsequently used to assess compliance. In some cases, chemical analysis was used to further evaluate sample integrity.
Supplementary Notes Sponsored by Environmental Protection Agency, Las Vegas, NV. National Exposure Research Lab.
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Category Codes 57U; 70; 92C
NTIS Prices PC A08
Primary Description 600/07
Document Type NT
Cataloging Source NTIS/MT
Control Number 029900450
Origin NTIS
Type CAT