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OLS Field Name OLS Field Data
Main Title Mechanisms of pesticide degradation /
Author Matsumura, Fumio.
Other Authors
Author Title of a Work
Moseman, Robert F.
CORP Author Wisconsin Univ., Madison. Dept. of Entomology.;Health Effects Research Lab., Research Triangle Park, NC.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory,
Year Published 1978
Report Number EPA/600/1-78/065; EPA-R-801060
Stock Number PB-289 776
Additional Subjects Pesticides ; Toxicity ; Degradation ; Molecular structures ; Anaerobic processes ; Chlorine organic compounds ; Laboratory animals ; Insecticides ; Separation ; Camphene ; Chemical analysis ; Bioassay ; Public health ; Toxaphene ; Chlordimeform ; Formamidine/N-(chloro-tolyl)-N-N-dimethyl ; Poly(bornane/chloro) ; Poly(bornene/chloro) ; Poly(tricyclene/chloro)
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
NTIS  PB-289 776 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation vii, 32 pages : illustrations ; 28 cm.
Abstract This research project was initiated with the overall objective of determining (1) the chemical structures of toxic components of toxaphene, (2) to study anaerobic metabolism to degrade toxaphene and other pesticides, and (3) to understand toxic action mechanism of chlordimeform. As a result of intensive efforts the molecular structures of three of the most toxic principles of toxaphene were identified. Together these components comprise at least 70% of toxaphene's toxicity toward mice. This is the first time that the structure of toxic components of toxaphene became apparent despite the widespread use (over 1 billion pounds, which is comparable to DDT) of toxaphene in the last 3 decades. Toxaphene on the other hand degrades relatively faster than other chlorinated pesticides such as DDT and dieldrin. The reason for it is that toxaphene is susceptible to reductive degradative forces. Chlordimeform was found to affect amine regulatory mechanisms in animals. Such actions explain some of the subtle effects of this pesticide on animals. Inasmuch as that biogenic amines are known to play many important biological roles such as controlling emotion, behavior and circulatory functions of the body.
Notes EPA Project Officer: Robert F. Moseman, Analytical Chemistry Branch, Environmental Toxicology Division, Health Effects Research Laboratory. Prepared by the Dept. of Entomology, University of Wisconsin, under Grant No. R-801060. "November 1978." Includes bibliographical references (pages 24-25). Microfiche.
Place Published Research Triangle Park, N.C.
Corporate Au Added Ent Health Effects Research Laboratory (Research Triangle Park, N.C.). Environmental Toxicology Division. Analytical Chemistry Branch.; United States. Environmental Protection Agency. Office of Research and Development.; University of Wisconsin--Madison. Dept. of Entomology.
PUB Date Free Form {1978}
Series Title Traced Research reporting series Environmental health effects research.
Series Title Untraced Research reporting series. 1, Environmental health effects research.
NTIS Prices PC A03/MF A01
BIB Level m
Medium microform
Cataloging Source OCLC/T
OCLC Time Stamp 20031209132030
Language eng
Origin NTIS
OCLC Rec Leader 01536nam 2200313Ka 45020