||Measurement of Blood Cholinesterase Activity in Laboratory Animals Utilizing Dimethylbutyl Acetate as a Substrate.
Cranmer, Morris F. ;
Peoples., Anita J. ;
||Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab.
||found in PB-280 889
||PB-280 902, found in PB-280 889
Acetic acid ;
Laboratory animals ;
Experimental data ;
Cholinesterase inhibitors ;
In vivo analysis ;
Blood chemical analysis ;
Acetic acid/butyl-dimethyl ;
Toxic substances ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||Blood cholinesterase activity was measured in the monkey, dog, rat, mouse, and rabbit. The use of the substrate, dimethyl butyl acetate, resulted in expected values for the monkey, dog, and rabbit, but the cholinesterase activity of the rat and mouse was quite elevated. In vivo cholinesterase inhibition resulted in lower values in all animals. Dimethyl butyl acetate was indicated an acceptable substrate for measuring cholinesterase activity except in the mouse and rat, where high levels of non-specific esterases complicated interpretation.
||contained in PB-280 889 titled Journal Articles on Toxicology. Group 14.
||Pub. in Laboratory Animal Science, v23 n5 p881-884 1973.
||Included in the report, Journal Articles on Toxicology, Group 14, PB-280 889.
||Reprint: Measurement of Blood Cholinesterase Activity in Laboratory Animals Utilizing Dimethylbutyl Acetate as a Substrate,
|PUB Date Free Form
||10 Jul 73
||6T; 57Y; 68E; 68G
||(Order as PB-280 889, MF A01)