||Investigation of selected potential environmental contaminants, Acrylonitrile : final report /
Miller, Lynne M. ;
Villaume., Jon E.
||Franklin Inst. Research Labs., Philadelphia, Pa.;Environmental Protection Agency, Washington, D.C. Office of Toxic Substances.
|| United States Environmental Protection Agency ; Reproduced [and distributed] by National Technical Information Service,
||EPA/560-2-78-003; FIRL-80G-C4807-01; FIRL-F-C4807-01; EPA-68-01-3893
Industrial medicine ;
Chemical industry ;
States(United States) ;
Foreign countries ;
Malignant neoplasms ;
Congenital abnormalities ;
Laboratory animals ;
Experimental data ;
Physiological effects ;
Literature surveys ;
Biological effects ;
Occupational safety and health ;
Air pollution effects(Humans) ;
Air pollution effects(Animals)
||OCSPP Chemical Library/Washington,DC
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||xii, 234 pages ; 28 cm
||The report is a survey and summary of the literature on acrylonitrile. Major aspects of its biological effects, environmental exposure, chemistry, production and use, and regulations are reviewed and assessed. Acrylonitrile is used in a wide variety of plastics, fibers, and elastomers. About 1.5 billion pounds of acrylonitrile are produced annually by the reaction of propylene, air, and ammonia. Low levels of acrylonitrile enter the environment during production, storage, end-product manufacture and end-use, although extensive monitoring data are not available. Recent evidence shows acrylonitrile to be carcinogenic in animals and possibly carcinogenic in humans. It resulted in birth defects when fed to pregnant rats and caused mutations in some type of bacteria. Short-term exposure to humans causes headache, mucus membrane irritation, dizziness, vomiting and incoordination. Several fatalities have resulted from fumigant use. Direct skin contact produces blisters resembling second-degree burns. In laboratory mammals, signs of acrylonitrile intoxication include altered breathing, incoordination, weakness, convulsions, and coma.
||"EPA/560-2-78-003." "May 1978." PB 285 881. Project Officer : Frank J. Letkiewicz Includes bibliographical references (pages 213-230). Final report ; Sponsored by Office of Toxic Substances, U.S. Environmental Protection Agency ;
||Washington, D.C. Springfield, Va.
|Corporate Au Added Ent
||United States. Environmental Protection Agency. Office of Toxic Substances.
|NTIS Title Notes
|PUB Date Free Form
||6T; 6J; 6F; 57Y#; 57U; 68G#; 68A
||PC A12/MF A01
|OCLC Time Stamp
|OCLC Rec Leader
||01707cam 2200421Ii 45020