Main Title |
Postnatal Alterations in Development Resulting from Prenatal Exposure to Pesticides. |
Author |
Kavlock, R. J. ;
Rogers, J. M. ;
Gray, L. E. ;
Chernoff, N. ;
|
CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1986 |
Report Number |
EPA/600/D-86/173; |
Stock Number |
PB86-229895 |
Additional Subjects |
Pesticides ;
Toxicology ;
Embryos ;
Exposure ;
Pregnancy ;
Morphology ;
Postnatal alterations
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB86-229895 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
15p |
Abstract |
Alterations in the developmental processes of embryos resulting from exposure to chemicals are not limited to morphological abnormalities that can be observed in the near term fetus. In the research on the developmental toxicology of pesticides the authors have noted morphological defects (cataracts, ablation of Harderian gland development, malformation of the otoliths) in postnatal offspring exposed prenatally that could not be detected in fetal examinations because of the immature nature of these structures at that stage of development. In addition, other effects on physiological functions have been detected (locomotor hyperactivity, and decreased renal concentrating ability) that have no obvious morphological basis. Thus, a postnatal component of a standard teratology bioassay can yield critical new information in the overall assessment of developmental toxicity. |
PUB Date Free Form |
Aug 86 |
Category Codes |
6T; 57Y |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
629615156 |
Origin |
NTIS |
Type |
CAT |