Main Title |
Effects of Chronic Exposure to 2, 3, 7, 8,-Tetrachlorodibenzo-p-Dioxin on Sister Chromatid Exchange Levels in Peripheral Lymphocytes of the Rhesus Monkey. |
Author |
Lim, M. ;
Jacobson-Kram, D. ;
Bowman, R. E. ;
Williams, J. R. ;
|
CORP Author |
Johns Hopkins Oncology Center, Baltimore, MD. Radiobiology Lab. ;Wisconsin Univ.-Madison.;Environmental Protection Agency, Washington, DC. Office of Research and Development. |
Year Published |
1987 |
Report Number |
EPA-R-812535 ;EPA-R-811685; EPA/600/J-87/360; |
Stock Number |
PB88-215264 |
Additional Subjects |
Toxicology ;
Hazardous materials ;
Laboratory animals ;
Monkeys ;
Chromosomes ;
Reprints ;
Toxic substances ;
Dibenzodioxin/tetrachloro ;
Chronic exposure ;
Chromosome aberrations ;
Lymphocytes ;
Cytogenetics
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB88-215264 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
8p |
Abstract |
Frequencies of sister chromatid exchanges and chromosomal aberrations were examined in peripheral lymphocytes of Rhesus monkeys that had been fed a diet containing 25 parts per trillion 2,3,7,8-tetrachlorodibenzo-p-dioxin for a period of 4 years. When compared to non-exposed control animals, no significant differences were noted for either of these cytogenetic end points. In addition, there was not a significant difference in sister chromatid exchange response to a challenge dose of mitomycin C in cells from 2,3,7,8-tetrachlorodibenzo-p-dioxin exposed animals compared to controls. The results confirm the lack of genotoxic effects associated with 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure. |
Supplementary Notes |
Pub. in Cell Biology and Toxicology, v3 n3 p279-284 1987. Prepared in cooperation with Wisconsin Univ.-Madison. Sponsored by Environmental Protection Agency, Washington, DC. Office of Research and Development. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Effects of Chronic Exposure to 2, 3, 7, 8,-Tetrachlorodibenzo-p-Dioxin on Sister Chromatid Exchange Levels in Peripheral Lymphocytes of the Rhesus Monkey. |
PUB Date Free Form |
c1987 |
Category Codes |
57Y; 57F; 57Z |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/21 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
826014324 |
Origin |
NTIS |
Type |
CAT |