||Studies on the Toxicity of O,O-Dimethyl-2,2-Dichlorovinyl Phosphate (DDVP).
Durham, William F. ;
Gaines, Thomas B. ;
McCauley, Robert H. ;
Sedlak, Vincent A. ;
Mattson., Arnold M. ;
||Communicable Disease Center, Atlanta, Ga.
Chlorine organic compounds ;
Laboratory animals ;
Experimental data ;
Lethal dosage ;
Respiratory system ;
Toxic substances ;
DDVP insecticide ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||The acute oral and dermal L.D.60 values of DDVP for male white rats were found to be 80 and 107 mg/kg, respectively. The corresponding values for females were 56 and 75 mg/kg. Pure DDVP was found, under the conditions studied, to be somewhat more toxic than the technical material. Feeding for 90 days on dietary levels of DDVP up to 1000 ppm caused no signs of intoxication in rats. However, dietary levels as low as 50 ppm produced definite lowering of plasma and erythrocyte cholinesterase levels. Monkeys confined for two weeks in Peet-Grady chambers which had been sprayed with 100 and 195 mg of DDVP per square foot showed depletion of both plasma and erythrocyte cholinesterase.
||Pub. in A. M. A. Archives of Industrial Health, v15 p340-349, Apr 57.
||Included in the report, Journal Articles on Toxicology. Group 3, PB-278 081.
||Reprint: Studies on the Toxicity of O,O-Dimethyl-2,2-Dichlorovinyl Phosphate (DDVP),
|PUB Date Free Form
||26 Nov 56
||6T; 57Y; 68E; 68G
||(Order as PB-278 081, MF A01)