Full Record Display for the EPA National Library Catalog

RECORD NUMBER: 6 OF 131

OLS Field Name OLS Field Data
Main Title Age-Related Alterations in the Stimulated Release In vitro of Catecholamines and Luteinizing Hormone-Releasing Hormone from the Male Rat Hypothalamus.
Author Goldman, J. M. ; Cooper, R. L. ; Rehnberg, G. L. ; Gabel, S. ; McElroy, W. K. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;National Inst. of Environmental Health Sciences, Research Triangle Park, NC.;Iowa Univ., Iowa City. Coll. of Medicine.
Year Published 1987
Report Number EPA/600/J-87/128;
Stock Number PB88-144423
Additional Subjects Catecholamines ; Aging(Biology) ; Hypothalamus ; Norepinephrine ; Dopamine ; Rats ; Tissues(Biology) ; Reprints ; LH-FSH releasing hormone ; Tissue culture ; Electric stimulation
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB88-144423 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/21/1988
Collation 9p
Abstract Using an in vitro perifusion system, the present study investigated the possibility that alterations in catecholamine and luteinizing hormone-releasing hormone (LHRH) secretion from the male rat mediobasal hypothalamus are present during the period of middle-age. The results indicate that, while tissue concentrations and baseline secretion of norepinephrine, dopamine and LHRH were similar between age groups, the patterns of dopamine and LHRH release in response to a series of depolarizing stimuli was different in the older animals. After all challenges, dopamine concentrations in the perifusate declined much more sharply for the middle-aged group, a finding that may be associated with a decrease with age in the pool of transmitter available for ready release. (Copyright (c) 1987 Plenum Publishing Corporation.)
Supplementary Notes Pub. in Neurochemical Research, v12 n7 p651-657 1987. Prepared in cooperation with National Inst. of Environmental Health Sciences, Research Triangle Park, NC. Sponsored by Iowa Univ., Iowa City. Coll. of Medicine.
NTIS Title Notes Journal article.
Title Annotations Reprint: Age-Related Alterations in the Stimulated Release In vitro of Catecholamines and Luteinizing Hormone-Releasing Hormone from the Male Rat Hypothalamus.
PUB Date Free Form c1987
Category Codes 57; 57S; 57I; 57B
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 808419207
Origin NTIS
Type CAT