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OLS Field Name OLS Field Data
Main Title Protein adduct forming chemicals for exposure monitoring : chemicals selected for further study /
Author Schnell, Frank C. ; Chiang, T. C.
Other Authors
Author Title of a Work
Chiang, Tom C.
Nauman, Charles H.
CORP Author Lockheed Engineering and Sciences Co., Inc., Las Vegas, NV.;Environmental Monitoring Systems Lab., Las Vegas, NV.
Publisher U.S. Environmental Protection Agency, Environmental Monitoring Systems Laboratory ; Available from the National Technical Information Service,
Year Published 1989
Report Number EPA/600/4-89/035; 68-03-3249; EPC-68-03-3249
Stock Number PB90-151762
OCLC Number 36679277
Subjects Chemicals--Testing. ; Toxicity testing--United States.
Additional Subjects Proteins ; Carcinogens ; Toxicity ; Hydrolysis ; Tables(Data) ; In vitro analysis ; In vivo analysis ; Hemoglobins ; Aromatic compounds ; Detoxification ; Diagrams ; Adducts ; Metabolic activation ; Dose-response relationships ; Environmental monitoring ; Environmental exposure pathways
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJED  EPA/600/4-89/035 OCSPP Chemical Library/Washington,DC 01/13/2001
ELBD  EPA 600-4-89-035 AWBERC Library/Cincinnati,OH 05/08/1998
NTIS  PB90-151762 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation vii, 169 p. : ill. ; 28 cm.
Abstract The present report is an in-depth characterization of twenty-two chemicals and the protein (primarily hemoglobin) adducts that are formed following exposure to these compounds. These chemicals were recommended for further study in a recent internal report which described the state of the science with regard to chemicals and adducts potentially of interest for exposure monitoring. The twenty-two compounds which are evaluated are ranked and placed in one of the following categories: (1) Simple alkylating and arylating agents that form N-terminal valine adducts, (2) Aromatic amines that form hydrolyzable cysteine adducts, (3) Chemicals that form hydrolyzable, but less well-characterized adducts, (4) Chemicals that form characterized, but nonhydrolyzable adducts, and (5) Chemicals that form poorly characterized adducts.
Notes "October 1989." "EPA/600/4-89/035." "Contract no. 68-03-3249." "Work assignment manager, Charles H. Nauman." Includes bibliographical references.
Place Published Las Vegas, Nev. Springfield, Va.
Supplementary Notes Sponsored by Environmental Monitoring Systems Lab., Las Vegas, NV.
Corporate Au Added Ent Lockheed Engineering & Sciences Company.; Environmental Monitoring Systems Laboratory (Las Vegas, Nev.); United States. Environmental Protection Agency. Office of Research and Development.
PUB Date Free Form 1989.
NTIS Prices PC A09/MF A01
BIB Level m
Cataloging Source OCLC/T
OCLC Time Stamp 20010111154226
Language eng
Origin OCLC
OCLC Rec Leader 01468nam 2200361Ka 45010