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OLS Field Name OLS Field Data
Main Title Scientific basis for the development of the international toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compounds /
Author Safe, S. H. ; Kutz, F. W. ; Bottimore, D. P.
Other Authors
Author Title of a Work
Safe, Stephen H.
Kutz, Frederick W.
Bottimore, David P.
CORP Author NATO Committee on the Challenges of Modern Society, Brussels (Belgium). ;Texas A and M Univ., College Station. ;Versar, Inc., Springfield, VA.;Environmental Protection Agency, Washington, DC.
Publisher U.S. Environmental Protection Agency, Office of research and Development ; Committee on the Challenges of Modern Society,
Year Published 1988
Report Number EPA/600/6-90/015; NATO/CCMS 178; EPA-68-02-4245
Stock Number PB91-109991
Subjects Dioxins.
Additional Subjects Dioxins ; Toxicity ; Pollution ; Bioassay ; Risk assessment ; Environmental impacts ; Dosage ; Response ; Rats ; Fly ash ; Pyrolysis ; Municipalities ; Concentration(Composition) ; Exposure ; Humans ; EC50 ; Polychlorinated dibenzo p-dioxins ; Dibenzofurans
Library Call Number Additional Info Location Last
NTIS  PB91-109991 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation 63 pages ; 28 cm.
Abstract The Pilot Study on International Information Exchange on Dioxins and Related Compounds was initiated to apply the cooperative efforts of several nations to address issues assoc. with PCDDs, PCDFs, and related compounds. The three-year study was conducted under the aegis of the CCMS of NATO. The report presents a detailed discussion of the scientific basis for the development of toxicity equivalency factors and provides the toxicity data and methodology used to determine the I-TEFs. Section 2 discusses background information on PCDDs and PCDFs. Section 3 discusses the need for I-TEFs. Section 4 presents the mechanisms of toxicity of these compounds. Section 5 provides a discussion of the development of TEFs from experimental toxicity data.
Notes Cover title. "Report of the NATO/CCMS Pilot Study on International Information Exchange on Dioxins and Related Compounds"--Page [i]. "December 1988"--Cover. "Contract No. 68-02-4254"--Page [i]. Includes bibliographical references (pages 46-56). Microfiche.
Place Published {Washington, DC} :
Supplementary Notes See also PB91-110007. Prepared in cooperation with Texas A and M Univ., College Station, and Versar, Inc., Springfield, VA. Sponsored by Environmental Protection Agency, Washington, DC.
Corporate Au Added Ent United States. Environmental Protection Agency. Office of Research and Development. ; Versar, Inc. ; North Atlantic Treaty Organization. Committee on the Challenges of Modern Society.
PUB Date Free Form 1988.
Series Title Traced NATO/CCMS (Series) ; no. 178
NTIS Prices PC A04/MF A01
BIB Level m
Cataloging Source OCLC/T
OCLC Time Stamp 20001219173512
Language eng
Origin NTIS
OCLC Rec Leader 01725nam 2200361Ka 45020