Full Record Display for the EPA National Library Catalog

RECORD NUMBER: 15 OF 15

OLS Field Name OLS Field Data
Main Title Study of Intermolecular Complexes of Bis (p-Chlorophenyl) Acetic Acid and Some Biologically Significant Compounds.
Author Ross, Ralph T. ; Biros., Francis J. ;
CORP Author Environmental Protection Agency, Perrine, Fla. Primate and Pesticides Effects Lab.
Year Published 1973
Stock Number PB-274 733
Additional Subjects Chlorine organic compounds ; Pesticides ; Nuclear magnetic resonance ; Molecular relaxation ; Toxicity ; DDT ; Insecticides ; Reprints ; Acetic acid/bis(chlorophenyl) ; Chemical shifts(Nuclear magnetic resonance)
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB-274 733 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 10p
Abstract The results of this investigation have shown that with the use of high resolution NMR relaxation measurement studies, some insight into the importance of molecular binding of p,p'-DDA with BSA and HSA may be obtained. The binding phenomena may be interpreted in terms of preferential stabilization of the aromatic rings by binding sites on the BSA and HSA molecules. This was demonstrated by the greater relaxation rates found for the aromatic protons of the p,p'-DDA than those of the alpha-methine proton. These relaxation rates were quite pD dependent as would be expected from a specific binding mechanism. The binding of p,p'-DDA.BSA and p,p'-DDA.HSA is hydrophobic in nature since a direct relationship was found with ionic strength and relaxation times. The relaxation rates of both complexes increase with decrease in temperature.
Supplementary Notes Pub. in Mass Spectrometry and NMR Spectroscopy in Pesticide Chemistry, n.d.
Availability Notes Included in the report, Journal Articles on Pesticide Chemistry, PB-274 732.
Title Annotations Reprint: A Study of Intermolecular Complexes of Bis (p-Chlorophenyl) Acetic Acid and Some Biologically Significant Compounds,
PUB Date Free Form 1973
Category Codes 7D; 6F; 99F; 57P
NTIS Prices (Order as PB-274 732, MF A01)
Primary Description 500/01
Document Type NT
Cataloging Source NTIS/MT
Control Number 323728418
Origin NTIS
Type CAT