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OLS Field Name OLS Field Data
Main Title Micronuclei and Other Nuclear Anomalies in Buccal Smears: Methods Development.
Author Tolbert, P. E. ; Shy, C. M. ; Allen, J. W. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Genetic Toxicology Div. ;North Carolina Univ. at Chapel Hill. School of Public Health.
Publisher c1992
Year Published 1992
Report Number EPA/600/J-92/446;
Stock Number PB93-141455
Additional Subjects Mouth ; Carcinogenesis ; Tobacco ; Micronucleus tests ; Smokeless tobacco ; Chromosome aberrations ; Epidemiologic methods ; Genetic markers ; Epithelial cells ; Public health ; Radiation effects ; Reprints ; Buccal smears ; Snuff
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB93-141455 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/12/1993
Collation 11p
Abstract Laboratory work aimed at improving the epidemiologic utility of an innovative genotoxicity marker is described. The exfoliated cell micronucleus assay involves microscope analysis of epithelial smears to determine the prevalence of micronucleation, an indicator of structural or numeric chromosomal aberrations. Exfoliated cells are moribund and undergo degenerative phenomena that can produce extranuclear objects difficult to distinguish from classical micronuclei. We also provide evidence that other nuclear anomalies are at least as common as micronucleation and that, therefore, there is the potential for extensive misclassification.
Supplementary Notes Pub. in Mutation Research, v271 n1 p69-77 Feb 92. See also PB93-141448. Prepared in cooperation with North Carolina Univ. at Chapel Hill. School of Public Health.
NTIS Title Notes Journal article.
Title Annotations Reprint: Micronuclei and Other Nuclear Anomalies in Buccal Smears: Methods Development.
Category Codes 57F; 57U
NTIS Prices PC A03/MF A01
Primary Description 600/10
Document Type NT
Cataloging Source NTIS/MT
Control Number 307031529
Origin NTIS
Type CAT