| Main Title |
Acute Toxicity of Pesticides in Adult and Weanling Rats. |
| Author |
Gaines, T. B. ;
Linder, R. E. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1986 |
| Report Number |
EPA/600/J-86/22; |
| Stock Number |
PB87-171062 |
| Additional Subjects |
Pesticides ;
Toxicity ;
Exposure ;
Environmental impact ;
Toxicology ;
Hazardous materials ;
Tests ;
Laboratory animals ;
Rats ;
Reprints ;
LD50 values ;
Health risk
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB87-171062 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
12p |
| Abstract |
LD sub 50 values were determined for 57 pesticides administered by the oral or dermal route to adult male and female Sherman rats. Nine pesticides tested by the oral route (bufencarb, cacodylic acid, dialifor, deltamethrin, dicamba, diquat, quintozene, phoxim, pyrazon) and 4 tested by the dermal route (bufencarb, chlordimeform, dichlofenthion, leptophos) were more toxic to females than to males whereas famphur and 2,4,5-T (oral route) were less toxic to females. Eighteen of the test chemicals were more toxic to the adult than to the weanling and 4 compounds (leptophos, methidathion, pyrazon and sulfoxide) were more toxic to the weanling. In additional studies the variability of the LD sub 50 value over a one year period was examined for 2 typical insecticides. Six consecutive bimonthly oral LD sub 50 determinations for parathion and DDT in adults of both sexes indicated that the LD sub 50 values were little affected by the time of year that the tests were done. |
| Supplementary Notes |
Pub. in Fundamental and Applied Toxicology 7, p299-308 1986. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Acute Toxicity of Pesticides in Adult and Weanling Rats. |
| PUB Date Free Form |
1986 |
| Category Codes |
68G; 68E; 57Y |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
718318406 |
| Origin |
NTIS |
| Type |
CAT |
