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RECORD NUMBER: 26 OF 65

Main Title Evaluation of 10 Chemicals for Aneuploidy Induction in the Hexaploid Wheat Assay.
Author Sandhu, S. S. ; Dhesi, J. S. ; Gill, B. S. ; Svendsgaard, D. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Genetic Toxicology Div. ;North Carolina Central Univ., Durham. Dept. of Biology. ;Environmental Health Research and Testing, Inc., Research Triangle Park, NC.
Publisher c1991
Year Published 1991
Report Number EPA/600/J-91/268;
Stock Number PB92-113307
Additional Subjects Aneuploidy ; Mutagens ; Wheat ; Mutagenicity tests ; Mitotic spindle apparatus ; Tables(Data) ; Bioassay ; Reprints ; Seedlings
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NTIS  PB92-113307 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 7p
Abstract The study was a part of an international project sponsored by the Commission of the European Communities to evaluate the utility of certain bioassays including hexaploid wheat assay to identify potential aneugens. Ten suspect spindle poisons, i.e. colchicine (COL), cadmium chloride (CdCl2), chloral hydrate (CH), diazepam (DIZ), econazole (EZ), hydroquinone (HQ), pyrimethamine (PY), thiabendazole (TB), thimerosal (TM), and vinblastin sulphate (VBL) were tested for their ability to induce green and/or white leaf sectors as indicators of loss or gain of a chromosome respectively, in Neatby's strain of Chinese Spring wheat (2n = 6x=42). All the chemicals tested in the study, with the exception of CH and HQ yielded positive response.
Supplementary Notes Pub. in Mutagenesis, v6 n5 p369-373 Sep 91. Prepared in cooperation with North Carolina Central Univ., Durham. Dept. of Biology, and Environmental Health Research and Testing, Inc., Research Triangle Park, NC.
NTIS Title Notes Journal article.
Title Annotations Reprint: Evaluation of 10 Chemicals for Aneuploidy Induction in the Hexaploid Wheat Assay.
Category Codes 57Y; 57F; 57C
NTIS Prices PC A02/MF A01
Primary Description 600/10
Document Type NT
Cataloging Source NTIS/MT
Control Number 135322327
Origin NTIS
Type CAT