| Main Title |
Effects of 4-ter-Octylphenol on Xenopus tropicalis in a Long Term Exposure. |
| Author |
K. L. Porter ;
A. W. Olmstead ;
D. M. Kumsher ;
W. E. Dennis ;
R. Sprando
|
| CORP Author |
Army Center for Environmental Health Research, Fort Detrick, MD. |
| Year Published |
2011 |
| Report Number |
EPA-IAG-DW-21-92262901-0 |
| Stock Number |
ADA553581 |
| Additional Subjects |
Estrogens ;
Exposure(Physiology) ;
Frogs ;
Receptor sites(Physiology) ;
Amphibians ;
Control ;
Induction systems ;
Ratios ;
Sampling ;
Sex ;
Sex glands ;
Time intervals ;
Water supplies ;
Xenopus tropicalis ;
Octylphenol estrogenic vitellogenin ;
Oviducts ;
Endocrine disruptor
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
ADA553581 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
47p |
| Abstract |
We exposed Xenopus tropicalis to 1, 3.3, 11 and 36 ug/L octylphenol from Neiuwkoop-Faber (NF) state 46 tadpoles through adulthood in a flow-through water system. At NF stage 5, a random subsample of froglets was collected and assessed, while the remaining frogs were exposed through 31 weeks. Significant induction of vitellogenin was observed in the high treatment at the larval subsampling for both sexes, but not at the final sampling for either sex. No significant deviation from control for sex ratio was observed for either sampling period, suggesting minimal to no effect on gonad differentiation. Oviduct development was observed in males exposed to octylphenol. These results indicate that octylphenol exposure can induce vitellogenin in immature froglets and the development of oviducts in male adult frogs. The lack of effect observed on the developing gonads suggests that in amphibians, secondary sex characteristics are more susceptible to estrogenic compounds than developing gonads. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5301 Shawnee Road, Alexandria, VA, 22312, USA. |
| PUB Date Free Form |
17 Mar 2011 |
| Category Codes |
57C; 57Z; 57E |
| NTIS Prices |
PC A04/MF A04 |
| Document Type |
NT |
| Medium |
Research rept |
| Cataloging Source |
NTIS/MT |
| Control Number |
111402080 |
| Origin |
NTIS |
| Type |
CAT |
