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RECORD NUMBER: 2804 OF 2869

Main Title Volatile organic compound emission controls for tablet coating at pharmaceutical plants /
Other Authors
Author Title of a Work
Glen, Eileen.
CORP Author PEDCo-Environmental, Inc., Arlington, TX.;Environmental Protection Agency, Philadelphia, PA. Region III.
Publisher EPA Region III,
Year Published 1984
Report Number PB84182922
Stock Number PB84-182922
OCLC Number 42630969
Subjects Volatile organic compounds--Environmental aspects ; Pharmaceutical industry--Environmental aspects ; Tableting--Environmental aspects ; Air--Pollution
Additional Subjects Air pollution control ; Drug industry ; Coating processes ; Tablets ; Activated carbon treatment ; Adsorption ; Volatile organic compounds ; Indoor air pollution
Internet Access
Description Access URL
https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=2000VT77.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EJAM  TD885.5.O74V68 1984 Region 3 Library/Philadelphia, PA 10/22/1999
NTIS  PB84-182922 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation iv, 21, [11] leaves ; 29 cm.
Abstract Pharmaceutical plants coat tablets with either a water-based or organic-based material in a batch operation that uses rotating open-ended pans. After being coated, the tablets are dried by hot air. Most tablets are coated with sugar, methyl cellulose, or ethyl cellulose. Because sugar coatings are water-based, they are not a source of volatile organic compound (VOC) emissions. Cellulose coatings can be applied either in water or in an organic media. An organic solvent is used if faster drying is required or if the tablet is sensitive to water and/or heat. This process is often referred to as film coating. The most practical VOC emission control method is adsorption of the VOC stream onto activated carbon. The pharmaceutical industry currently uses this method to control VOC emissions from tablet coating operations. Carbon adsorbers are rugged and simple to operate, and the recovered methylene chloride or chloroform is suitable for reuse without further treatment. Ethanol and isopropanol are recovered in dilute aqueous solutions that can be processed in the plant wastewater treatment facility. Incineration and refrigeration control methods are technically feasible, but uneconomic.
Notes "January 1984." Contract no. 68-02-3512, task order no. 43; project officer Eileen Glen. Includes bibliographical references (p. 21).
Place Published Philadelphia, PA
Corporate Au Added Ent Pedco Environmental, inc.; United States. Environmental Protection Agency. Region III.
PUB Date Free Form 1984.
BIB Level m
Cataloging Source OCLC/T
OCLC Time Stamp 19991013101025
Language eng
Origin OCLC
Type MERGE
OCLC Rec Leader 01045nam 2200277Ia 45020