Main Title |
Initial Submission: Teratology Screen in Rats (c-180, C-181, C-182, C-236, C-253, C-254, C-255, C-256, C-257, C-258, C-259) (Final Report) with Attachments and Cover Letter. |
CORP Author |
Hazleton Labs., Falls Church, VA.; Hoechst Celanese Corp., Summit, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
Year Published |
1991 |
Report Number |
88-920000178 |
Stock Number |
OTS0534628 |
Additional Subjects |
Toxicology ;
Health effects ;
Valeric Acid ;
Reproduction/fertility Effects ;
Teratogenicity ;
Mammals ;
Rats ;
Oral ;
Gavage ;
Toxic substances ;
Laboratory animals ;
CAS No 109-52-4
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Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
OTS0534628 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
128p |
Abstract |
Valeric acid (C-180; 109-52-4) was evaluated for developmental effects in 22 female Crl:COBS, CD(SD)BR rats administered 750 mg/kg of the test substance by gavage on days 6 through 15 of gestation. A control group received corn oil. Maternal animals showed an increased incidence of clinical observations (specific signs not reported). Offspring showed an increased incidence of delayed ossification of several bone structures. |
Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with Hoechst Celanese Corp., Summit, NJ. |
Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
PUB Date Free Form |
1991 |
Category Codes |
57Y; 57U; 68G; 99; 44G |
NTIS Prices |
PC A08/MF A08 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
028803260 |
Origin |
NTIS |
Type |
CAT |