Main Title |
Evaluation of Renal Function in Neonatal Rats. |
Author |
Kavlock, Robert J. ;
Gray, Jacqueline A. ;
|
CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1982 |
Report Number |
EPA-600/J-81-169; |
Stock Number |
PB83-209700 |
Additional Subjects |
Urologic diseases ;
Renal failure ;
Rats ;
Laboratory animals ;
Reprints ;
Ontogenesis ;
Neonatology
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB83-209700 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
12p |
Abstract |
The ontogenetic profile of several parameters of neonatal renal development in the rat is presented. Nephrogenesis was observed to continue at a rapid pace between birth and 8 days of age and to be virtually complete by 11 days of age. The activity of alkaline phosphatase, a brush border enzyme, declined during this time period relative to organ growth as a whole. The ability to elaborate a concentrated urine when presented with a period of fluid deprivation was barely present at birth and increased dramatically with age. Finally, the diuresis response to an orally administered water load was detected on the second post-natal day, while the response to antidiuretic hormones was present to a slight degree on the first postnatal day. |
Supplementary Notes |
Pub. in Biology of the Neonate p279-288 1982. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Evaluation of Renal Function in Neonatal Rats. |
PUB Date Free Form |
1982 |
Category Codes |
6P; 57S |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
324622609 |
Origin |
NTIS |
Type |
CAT |