| Main Title |
Acute Vapor Inhalation Study in Fischer 344 Rats Using Aerothene Tt with Cover Letter Dated 03/22/1988. |
| CORP Author |
Dow Chemical Co., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1988 |
| Report Number |
86-880000173 |
| Stock Number |
OTS0514062 |
| Additional Subjects |
Toxicology ;
Health effects ;
1 ;
1 ;
1-trichloroethane (71-55-6) ;
Acute Toxicity ;
Mammals ;
Rats ;
Inhalation ;
Toxic substances ;
Laboratory animals ;
CAS No 71-55-6
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0514062 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
34p |
| Abstract |
Acute inhalation toxicity was evaluated in groups of 5 male and 5 female Fischer 344 rats exposed to Aerothene TT (1,1,1-trichloroethane) at actual concentrations of 15,523, 18,425, or 21,063 ppm for 4 hours. Mortality was observed in 3 females in the 18,425 ppm dose group and all animals in the highest dose group. The LC50 value was reported to be between 18,425 - 21,063 ppm for males and calculated to be 18,000 ppm (16,600-19,400 ppm 95% confidence limits) for females by the moving average method. Clinical observations included lethargy and unresponsiveness. Gross necropsy revealed clear facial soiling and visceral congestion. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1988 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A04/MF A04 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028801890 |
| Origin |
NTIS |
| Type |
CAT |
