| Main Title |
Evaluation of the potential carcinogenicity of 4-chloro-o-toluidine hydrochloride (3165-93-3) / |
| CORP Author |
Syracuse Research Corp., NY. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. |
| Publisher |
U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ; |
| Year Published |
1988 |
| Report Number |
EPA/600/8-91/092; EPA-68-03-3112; EPA-68-03-3182; OHEA-C-073-056 |
| Stock Number |
PB93-185130 |
| Subjects |
Aromatic compounds--Carcinogenicity ;
4-chloro-o-toluidine hydrochloride--Carcinogenicity
|
| Additional Subjects |
Toxicity ;
Risk assessment ;
Public health ;
Exposure ;
Neoplasms ;
Hazardous materials ;
Tolerances(Physiology) ;
Toluidine/chloro-(hydrochloride) ;
Carcinogenicity ;
Dose-response relationships ;
CAS Registry No 3165-93-3
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB93-185130 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
18 pages ; 28 cm |
| Abstract |
4-Chloro-o-toluidine hydrochloride is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is 'Sufficient,' and the evidence from human studies is 'No Data.' The potency factor (F) for 4-chloro-o-toluidine hydrochloride is estimated to be 0.40 (mg/kg/day)(-1), placing it in potency group 3 according to the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and the potency group, 4-chloro-o-toluidine hydrochloride is assigned a 'LOW' hazard ranking. |
| Notes |
Cover title. "June 1988." Includes bibliographical references. Microfiche. |
| Place Published |
Washington, D.C. : |
| Supplementary Notes |
See also PB-295 864. Prepared in cooperation with Environmental Monitoring and Services, Inc., Washington, DC. Sponsored by Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. |
| Corporate Au Added Ent |
United States. Environmental Protection Agency. Office of Health and Environmental Assessment. Carcinogen Assessment Group. |
| PUB Date Free Form |
{1988} |
| NTIS Prices |
PC A03/MF A01 |
| BIB Level |
m |
| Cataloging Source |
OCLC/T |
| OCLC Time Stamp |
20010328180851 |
| Language |
eng |
| Origin |
NTIS |
| Type |
MERGE |
| OCLC Rec Leader |
01240nam 2200265Ka 45020 |
