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OLS Field Name OLS Field Data
Main Title Evidence That Drug-Resistant Alloreactive T Cells May Contribute to Human Graft Rejection.
Author Stanford, W. L. ; Strauss, G. H. S. ; Finn., O. J. ;
CORP Author Duke Univ., Durham, NC.;National Institutes of Health, Bethesda, MD.;Environmental Protection Agency, Washington, DC.
Publisher c1990
Year Published 1990
Report Number PO1-AI19368; EPA/600/J-90/175;
Stock Number PB91-115774
Additional Subjects Humans ; Reprints ; T lymphocytes ; Homologous transplantation ; Graft rejection ; Immunosuppressive agents ; Drug resistance ; Azathioprine ; Autoradiography
Library Call Number Additional Info Location Last
NTIS  PB91-115774 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 03/04/1991
Collation 6p
Abstract The objective of the study was to determine whether resistance to immunosuppressive drugs by transplant recipient's T cells could contribute to continued graft rejection, in spite of immunosuppressive therapy. The T cell lines used in the series of experiments were originally established from T cells that had infiltrated kidney or liver grafts and initiated rejections in patients receiving immunosuppressive drugs, including the purine analogue azathioprine (AZ). The authors have used a proliferation assay and the Strauss-Albertini test to analyze the T cell lines. Both assays use 6-thioguanine (6-TG), an amino derivative of AZ, as the selective agent to measure the resistance to AZ. (Copyright (c) 1990 by Williams and Wilkins.)
Supplementary Notes Pub. in Transplantation, v49 n6 p1138-1141 Jun 90. Sponsored by National Institutes of Health, Bethesda, MD., and Environmental Protection Agency, Washington, DC.
NTIS Title Notes Journal article.
Title Annotations Reprint: Evidence That Drug-Resistant Alloreactive T Cells May Contribute to Human Graft Rejection.
Category Codes 57Q; 57I; 57F; 57X
NTIS Prices PC A02/MF A01
Primary Description 100/00
Document Type NT
Cataloging Source NTIS/MT
Control Number 101123231
Origin NTIS
Type CAT