| Main Title |
Exposure of Humans to Carbon Monoxide Combined with Ingestion of Diphenhydramine Hydrochloride or Phenacetin. |
| CORP Author |
Medical Coll. of Wisconsin, Milwaukee. Dept. of Environmental Medicine.;Coordinating Research Council, Inc., New York. |
| Year Published |
1974 |
| Report Number |
MCOW-ENVM-CO-74-1; APRAC-CAPM-3-68; CRC-APRAC-CAPM-3-68-5; |
| Stock Number |
PB-242 098 |
| Additional Subjects |
Carbon monoxide ;
Drugs ;
Phenacetin ;
Toxicity ;
Exposure ;
Air pollution ;
Health ;
Pharmacology ;
Analgesics ;
Antihistamines ;
Performance(Human) ;
Synergism ;
Carbonylhemoglobin ;
Air pollution effects(Humans) ;
Diphenhydramine
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB-242 098 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
81p |
| Abstract |
The synergistic effect of CO and two commonly prescribed drugs, phenacetin and diphenhydramine hydrochloride were evaluated. The COHb saturation tested was 14 percent (above average for cigarette smokers), while drug doses were those usually prescribed. No synergistic effects were observed in the study. Three additional observations were made: (1) the occurrence of CO induced headaches at COHb saturations of 14 percent; (2) the possible effect of CO exposure on EEG activity at this level; and (3) the finding that phenacetin, as an analgesic, did not lessen the headaches induced by the CO exposure. |
| Highlights Notes |
Investigates synergistic effects of CO and two commonly prescribed drugs. |
| NTIS Title Notes |
Final rept. |
| PUB Date Free Form |
14 Aug 74 |
| Category Codes |
06T; 06O; 13B; 57Y#; 57Q; 68G#; 68A |
| NTIS Prices |
PC A05/MF A01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
326605259 |
| Origin |
NTIS |
| Type |
CAT |
