Main Title |
In vitro Screening Batteries for Neurotoxicants (Journal Article). |
Author |
Veronesi, B. ;
|
CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. Neurotoxicology Div. |
Publisher |
c1992 |
Year Published |
1992 |
Report Number |
EPA/600/J-92/260; |
Stock Number |
PB92-206408 |
Additional Subjects |
Toxicology ;
Nervous system ;
In vitro analysis ;
Tissue culture ;
Cell line ;
Cultured tumor cells ;
Scanning electron microscopy ;
Cell survival ;
Reprints ;
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB92-206408 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
12p |
Abstract |
The need to develop, validate and utilize in vitro models to test chemicals for neurotoxic potential is widely appreciated. The lecture discusses the major advantages of using cell and tissue culture, the various in vitro models amenable for neurotoxicity studies, and the distinction between mechanistic and screening models. Considerations for designing screening batteries to evaluate neurotoxicants are discussed. Topics such as choice of appropriate cell models and endpoints (i.e. cytotoxic and neurotoxic), and technical considerations in the design of the battery are also presented. (Copyright (c) 1992 by Intox Press, Inc.) |
Supplementary Notes |
Pub. in NeuroToxicology 13, p185-196 1992. See also PB91-231233. Presented at the Meeting of the International Neurotoxicology Association (3rd), Parma, Italy, July 1-5, 1991. |
Title Annotations |
Reprint: In vitro Screening Batteries for Neurotoxicants (Journal Article). |
Category Codes |
57Y |
NTIS Prices |
PC A03/MF A01 |
Primary Description |
600/10 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
226924095 |
Origin |
NTIS |
Type |
CAT |