| Main Title |
Role of Steroid Hormones and Decidual Induction in the Regulation of Adenosine Diphosphoribosyl Transferase Activity in Rat Endometrium. |
| Author |
Cummings., A. M. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
| Publisher |
c1989 |
| Year Published |
1989 |
| Report Number |
EPA/600/J-89/210; |
| Stock Number |
PB90-146218 |
| Additional Subjects |
Steroids ;
Hormones ;
Transferases ;
Rats ;
Deoxyribonucleic acids ;
Estrogens ;
Graphs(Charts) ;
Enzymes ;
Cell nucleus ;
Reprints ;
Endometrium ;
Adenosine diphosphate ribase ;
Dose-response relationships ;
NAD
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB90-146218 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
10p |
| Abstract |
To assess the effect of ovarian steroid hormones on enzyme activity, adenosine diphosphoribosyl transferase (ADPRT) was measured in endometrial nuclei isolated on estrus and on d 4 from rats ovariectomized on estrus (d 0) and treated d 0-3 with vehicle, 1 microg estrone/d (E), 1 mg progesterone on d 0 and 2 mg d 1-3 (P), or the 2 hormones combined (E+P). Decidual induction in rats treated with E+P through d 8 demonstrated the ability of the combination treatment to support a decidual response comparable to that of pseudopregnancy. Characteristics of ADPRT were assessed by the determination of assay optima, and the identity of the reaction product as poly(ADP-ribose) was confirmed. Deoxyribonuclease-stimulated activity (total) was higher than non-stimulated ADPRT activity (endogenous) in all assays except on estrus. Estrone treatment produced an increase in ADPRT activity accompanied by increased DNA content, tissue mass, and total protein. (Copyright (c) 1989 The Endocrine Society.) |
| Supplementary Notes |
Pub. in Endocrinology 124, n3 p1408-1416 1989. Presented at the Annual Meetings of the Society for the Study of Reproduction (20th and 21st). |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Role of Steroid Hormones and Decidual Induction in the Regulation of Adenosine Diphosphoribosyl Transferase Activity in Rat Endometrium. |
| Category Codes |
57B; 57F; 57Q |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/10 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
005324133 |
| Origin |
NTIS |
| Type |
CAT |
