| Main Title |
Analyzing Repeated Measurements with Possibly Missing Observations by Modelling Marginal Distributions. |
| Author |
Wei, L. J. ;
Stram., D. O. ;
|
| CORP Author |
Michigan Univ., Ann Arbor. Dept. of Biostatistics. ;Radiation Effects Research Foundation, Hiroshima (Japan).;Health Effects Research Lab., Research Triangle Park, NC. |
| Publisher |
c1988 |
| Year Published |
1988 |
| Report Number |
EPA-R-813495; EPA/600/J-88/523; |
| Stock Number |
PB90-232299 |
| Additional Subjects |
Biostatistics ;
Mathematical models ;
Biomathematics ;
Statistical analysis ;
Statistical distributions ;
Reprints ;
Health statistics
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB90-232299 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
12p |
| Abstract |
Suppose that subjects are observed repeatedly over a common set of time points with possibly time-dependent covariates and possibly missing observations. At each time point, the authors model the marginal distribution of the response variable and the effect of the covariates on that distribution using a class of quasi-likelihood models. No parametric model of dependence of the repeated observations of the subject is assumed. For large samples, the quasi-likelihood estimates of the time-specific regression coefficients over the set of predetermined time points are shown to be approximately jointly normal. This, coupled with various inference procedures, provides a global picture about the effects of the covariates on the response variable over the entire study period. A lack-of-fit test for testing the adequacy of the assumed quasi-likelihood model is also provided. All the methods considered are illustrated with real-life examples. (Copyright (c) 1988 by John Wiley & Sons, Ltd.) |
| Supplementary Notes |
Pub. in Statistics in Medicine, v7 p139-148 Feb 88. Prepared in cooperation with Radiation Effects Research Foundation, Hiroshima (Japan). Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Analyzing Repeated Measurements with Possibly Missing Observations by Modelling Marginal Distributions. |
| Category Codes |
57U; 72F |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/10 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
022221267 |
| Origin |
NTIS |
| Type |
CAT |
