| Main Title |
Effect of Solvent and Extraction Methods on the Bacterial Mutagenicity of Sidestream Cigarette Smoke. |
| Author |
Morin, R. S. ;
Tulis, J. J. ;
Claxton, L. D. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. Genetic Bioassay Branch. ;North Carolina Univ. at Chapel Hill. School of Public Health. |
| Year Published |
1987 |
| Report Number |
EPA/600/J-87/256; |
| Stock Number |
PB88-182381 |
| Additional Subjects |
Mutagens ;
Bacteria ;
Solvent extraction ;
Smoke ;
Air pollution ;
Toxicity ;
Cigarettes ;
Genetics ;
Particles ;
Laboratories ;
Metabolism ;
Salmonella ;
Activation ;
Agitation ;
Ultrasonic frequencies ;
Acetone ;
Carbinols ;
Chloromethanes ;
Reprints ;
Controlled burning ;
Ames test ;
Salmonella typhimurium
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB88-182381 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
15p |
| Abstract |
The mutagenic activity of sidestream cigarette smoke particles was estimated by testing sidestream cigarette smoke particles which had been collected under controlled burning conditions in the laboratory. Two different extraction methods (Soxhlet and ultrasonic agitation) and 3 different solvents (dichloromethane, methanol, and acetone) were compared for their efficiencies in the extraction of compounds from sidestream cigarette smoke particles which are mutagenic in the Ames test. The mutagenic activity of the sidestream smoke particles was estimated to be 15,000-20,000 revertants per cigarette in TA98 with metabolic activation and 12,000-17,000 revertants per cigarette in TA100 without metabolic activation. (Copyright (c) 1987 Elsevier Science Publishers B.V. (Biomedical Division).) |
| Supplementary Notes |
Pub. in Toxicology Letters, v38 p279-290 1987. Prepared in cooperation with North Carolina Univ. at Chapel Hill. School of Public Health. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Effect of Solvent and Extraction Methods on the Bacterial Mutagenicity of Sidestream Cigarette Smoke. |
| PUB Date Free Form |
c1987 |
| Category Codes |
68A#; 57Y#; 57K; 99D |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
814619702 |
| Origin |
NTIS |
| Type |
CAT |
